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4-amino-1,8-Naphthalimide,1742-95-6,6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione
发布时间:2023-03-20     作者:hao   分享到:
护肤商品编码称:4-amino-1,8-Naphthalimide,1742-95-6,6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione产自:咸阳型号:1mg 5mg 10mg溶解度:99%的用途:仅用到教学科研贴心提醒:仅用作科研管理,不会用作躯干实验性!The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.1,2 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).3 It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.4 4-ANI is used to study the role of PARP activity in various cell systems.

4-amino-1,8-Naphthalimide,1742-95-6,6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione

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