PJ-34 (hydrochloride),344458-15-7
厂称呼称:PJ-34 (hydrochloride),344458-15-7产区:绵阳年纪:1mg 5mg 10mg色度:99%应用:仅用作成果转化溫馨显示信息:仅使用科研开发,不要使用人的身体实验英文!The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.1,2 PJ-34 is an inhibitor of PARPs which can be used in cells or in animals.3,4,5 It binds and inhibits the PARP tankyrase1 (IC50 = 1 μM).6 PJ-34 also inhibits matrix metalloproteinase-2 when used at higher concentrations (IC50 = 56 μM).