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DSPE-PEG-TPP功能化MoS₂量子点的构建与表征
发布时间:2025-07-23     作者:zyl   分享到:
论文:The role of MoS2 QDs coated with DSPE-PEG-TPP in the protection of protein secondary structure of the brain tissues in an Alzheimer's disease model小说作者:Ohoud Abdulaziz Alamri a b, Safaa Qusti b, Maha Balgoon b, Abeer A. Ageeli c, F.A. Al-Marhaby d, Abeer M. Alosaimi e, Mohammed A. Jowhari f, Abdu Saeed g 论文资料链接代码: 内容提要:In a recent groundbreaking study [13], a pioneering approach was employed utilizing MoS2 QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(poly-ethyleneglycol)-2000] (DPSE-PEG) linked with (3-carboxypropyl)triphenylphosphonium bromide (TPP). This innovative compound, recognized for its novel mitochondria-targeted properties, represents a potential therapeutic avenue for AD treatment [13]. The strategic DSPE-PEG-TPP coating layer serves as an essential interface, facilitating the attachment of MoS2 QDs to the mitochondria of microglia cells within brain tissues. Our present investigation builds upon this paradigm, delving into the intricate role of MoS2 coated with DSPE-PEG-TPP in safeguarding the protein secondary structure within brain tissues. Moreover, a comprehensive exploration of the impact of DSPE-PEG-TPP-MoS2 QDs treatment on a spectrum of biomarkers has been meticulously undertaken. Further elucidation of the methodology, detailed results, and an in-depth analysis can be found in subsequent sections, offering a comprehensive understanding of our study. This study sheds light on the role of MoS2 QD in the protection of the protein secondary structure of the brain tissues against AD etiology.

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用于一种缔造性的的方法,利用率涂有1,2-二硬脂酰基-sn-甘油-3-磷无水乙醇胺-N-[氨基(聚乙二醇)-2000](DPSE-PEG)的MoS2量子点,与(3-羧丙基)三苯基溴化鏻(TPP)衔接。那样科技创新类化合物因为本身有趣的线粒体靶向药物基本特征而面临承认,代表会了阿尔茨海默病的隐藏的治疗方法渠道。的人才战略的DSPE-PEG-TPP表层就是个重要性的接口,有利于MoS2-QD粘附在脑结构内小胶质人体细胞的线粒体上。让我们阶段的探究建造在某种范式的根基上,深入细致探究了涂有DSPE-PEG-TPP的MoS2在保护英文脑团体内蛋白酶质特殊机构地方的多样化反应。最后,对DSPE-PEG-TPP-MoS2量子点中药治疗对一国产生态学标制物的反应开始了推进改革的深入研究。放前续章节目录中需要进一大步系统阐述步骤、详细进行分析报告单和渗入进行分析,所以多方位了解公司的科学科研。本科学科研具体分析了MoS2-QD在保证脑策划 蛋白酶质一级结构设计遭受AD病机直接影响这方面的的功效。有关于推介:mPEG-RGDmPEG-SS-CELmPEG-PLGA(30K)mPEG-PLGA(75:25)(5K)mPEG-DTA (ALC-0159) CAS No.: 1849616-42-7mPEG-DMG CAS No.: 160743-62-4mPEG-NBmPEG-PLA(15K)mPEG-PLGA(1K)mPEG-PLGA(10K)mPEG-PLGA(20K)mPEG-PEI(1K)以上的篇文章方式來源各大期刊杂志或参考文献,予以侵权行为请建立联系当我们删了!