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DSPE-PEG-iRGD修饰红细胞的制备及体外稳定性评估
发布时间:2025-07-14     作者:kx   分享到:
论文参考文献:红体细胞内化精氨酸-甘氨酸-天冬氨酸(iRGD)掩盖开展胃溃疡牵扯*药效友链://pmc.ncbi.nlm.nih.gov/articles/PMC9660045/小说作者:周冲 ,刘勤 ,孟凡彦 ,丁乃清 ,景艳 ,刘宝瑞节选:使用1,2-二硬脂酰-sn-甘油-3-磷酸乙酸乙酯胺-聚乙二醇-iRGD(DSPE-PEG-iRGD)凭借脂质读取法表达血体血血人体上皮细胞膜膜(RBC),需不需要一直化学物质生物学偶联。凭借共焦聚电子显微镜关察荧光染剂示踪职能性血体血血人体上皮细胞膜膜。休外固明确监测:将血体血血人体上皮细胞膜膜放置于体血血人体上皮细胞膜膜培养教育基中孵育48h,并且实行荧光衰减试验报告。最后,勾勒了MKN-45体血血人体上皮细胞膜膜皮下组织移植成功癌体血血人体上皮细胞膜膜小鼠建模 ,以监测DSPE-PEG-iRGD表达血体血血人体上皮细胞膜膜(RBC-iRGD)的靶向治疗疗法药物和靶向治疗疗法怎强相应。

DSPE-PEG-iRGD

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-poly ethylene glycol-iRGD (DSPE-PEG-iRGD) was used to modify RBCs by a lipid-insertion method without direct chemical bioconjugation. Fluorescent dyes were used to trace the functional RBCs through confocal microscopy examination. In vitro stability evaluation was performed using cell culture medium incubation for 48 h followed by fluorescence decay assay. Furthermore, a subcutaneous cancer cell mouse model was constructed with MKN-45 cells for target efficacy and RT enhancement evaluation with DSPE-PEG-iRGD-modified RBCs (RBC-iRGD).武汉pg电子娱乐游戏app 生物学具备有关护肤品:DSPE-PEG-EstrogenDMPE-PEG-SilaneDSPE-PEG-PyreneDSPE-PEG-SilaneDSPE-PEG-Dextranm-PEG8-DSPEDSPE-PEG-HisPeptides PEG PCL以上的稿件介绍渠道当下学术期刊或资料,请谅解抄袭请沟通我们都去除!