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聚合物-多肽/蛋白质共聚物
发布时间:2020-10-16     作者:wyf   分享到:

表面层上的聚合反应物-多肽/淀粉酶质共聚物

从文中阐述了单单从表面共价接枝的多肽/蛋清质的合成视频具体方式 以至于初中物理、生物学表现技术水平。兑换这样表层接枝的核心具体方式 以及配位高分子化合物链的“嫁打电话(grafting to)”或“融合于(grafting from)”手段,以来再黏附肽/球膳食纤维。还有行将制作网站的合成图片物移植后到面上。

Abstract:

Background: Polymer-peptide/protein conjugates immobilized on surface have gained considerable attention, mostly due to their broad scope of applications in biomedical fields. To optimize their properties, the combined knowledge of polymer chemistry and biochemistry has to be applied.

Method: The main methods to obtain such surfaces involve “grafting to” or “grafting from” of polymeric linkers with subsequent attachment of a peptide/protein. Alternatively, a “ready-made” conjugate may be grafted to the surface.

Result: The structure of the polymer linker significantly influences the properties of the active surface, and a variety of physicochemical methods and tools have been successfully applied to study the structure-property relationship of these surfaces.

Conclusion: This review outlines the applied synthetic strategies leading to covalently attached bioconjugates on the surface and the characterization techniques used to study those materials. The relevance of different linear polymeric linkers and their influence on the properties of the obtained materials is discussed.

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