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SPDP-PEG-DBCO DBCO-PEG20000-SPDP 异双功能 PEG试剂介绍
发布时间:2023-05-26     作者:LYQ   分享到:
常常明称:二苯并环辛炔-聚乙二醇-3-(2-吡啶二硫代)丙酸N-羟基虎珀酰亚胺酯英文音标各称:DBCO-PEG-SPDP;SPDP-PEG-DBCOProduct description:SPDP first reacts with a protein molecule via its amino group. SPDP introduces pyridine disulfide into the protein, and then the pyridine disulfide is reduced by DTT to form mercaptan group. These mercaptan groups then form a disulfide bond with another protein molecule to produce heterodimer proteins.

SPDP结构式:

DBCO (dibenzocyclooctene) is a cycloalkyne, which can react with azide through 1,3-dipolar cycloaddition promoted by strain in aqueous solution, which is a biorthogonal reaction, also known as copper free click reaction. The selectivity and biocompatibility of this reaction enable complementary reagents to form covalent bonds with functional biological systems. Copper free click reaction is a powerful tool for biocoupling without catalyst. DBCO reagent has fast kinetics and stability in water buffer, and can be used to label azide modified biomolecules with high specificity and reactivity.看:固体颗粒或沾性气体,考量于原子核量端基转变率:≥95%借款用途:仅中用科学理论研究理论研究并且工业制造运用等非医用目的意义,非入药,非吃特别留意问题:移取必定要皮肤干燥,防止频频的溶解性和冻干降解性:分解大要素可挥发液体,如:DCM、DMF、DMSO、THF这些。在水含有非常不错的降解性的护肤品推存:

MA-PEG-SC

HO-PEG-SCMAlkyne-PEG-SCAA-PEG-SVAAA-PEG-SC8-arm PEG-SSA(TP)8-arm PEG-SSA(HG)8-arm PEG-SS(TP)8-arm PEG-SS(HG)8-arm PEG-SGA(TP)