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Isorhynchophylline,6859-01-4
发布时间:2023-03-20     作者:hao   分享到:
商产品品牌称:Isorhynchophylline,6859-01-4产区:石家庄技术参数:1mg 5mg 10mg饱和度:99%使用:仅用来科技创新和谐提醒:仅使用科研课题,不许使用身休实验性!Isorhynchophylline is an oxindole alkaloid that has been found in Uncaria and has diverse biological activities, including neuroprotective, anticancer, and antihypertensive properties.1,2,3,4 It inhibits decreases in cell viability and increases in intracellular levels of reactive oxygen species (ROS) and malondialdehyde (MDA) induced by amyloid-β (25-35) (Aβ (25-35); Item No. 24155) in PC12 cells in a concentration-dependent manner.1 Isorhynchophylline (30 and 100 μM) attenuates decreases in population spike amplitudes in the CA1 region of a rat hippocampal slice model of ischemia induced by oxygen and D-glucose deprivation.2 It decreases the viability of HepG2, A549, BxPC-3, Caki-1, RPMI-8226, and 786-O cells (IC50s = 130-292 μM).3 In HepG2 cells, isorhynchophylline induces apoptosis, inhibits cell migration in a wound healing assay, and decreases invasion in a Matrigel™ assay. Isorhynchophylline (0.1% in the diet) decreases right ventricular end systolic pressure, hypertrophy, and fibrosis in a rat model of pulmonary arterial hypertension induced by monocrotaline (Item No. 16666).4

Isorhynchophylline,6859-01-4

涉及新产品:JX06,729-46-4,4,4′-(dithiodicarbonothioyl)bis-morpholineTheaflavin,4670-05-7Ginsenoside Rb3,68406-26-8插入图片:XAQYBIO HAO,202两年多4月十五日。