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Dieugenol,4433-08-3
发布时间:2023-03-20     作者:hao   分享到:
厂商品名字称:Dieugenol,4433-08-3制造地:杭州外形尺寸:1mg 5mg 10mg色度:99%作用:仅适用于科技研究贴心提示卡:仅使使用在科研工作,没有使使用在身休工作!Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities.1,2 It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays.1 It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s = 15.1 and 11.5 µM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 µM.2 Dieugenol (15 µM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.

Dieugenol,4433-08-3

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