ME0328,1445251-22-8
车辆各称:ME0328,1445251-22-8产自:北京要求:1mg 5mg 10mg含量:99%使用:仅中用教育科研浪漫信息提示:仅使用在科学研究,没能使用在人實驗!The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species.1,2 ME0328 is an inhibitor of PARP3 (IC50 = 0.89 µM), which is a regulator of DNA repair and mitotic progression.3 It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.