9(E),11(E),13(E)-Octadecatrienoic Acid,544-73-0
车辆英文名称:9(E),11(E),13(E)-Octadecatrienoic Acid,544-73-0原产地:上海金桥铜业跨接线的截面积大小:1mg 5mg 10mg溶解度:99%领域:仅广泛用于成果转化温磬表示:仅于科学,不要于人休实践!9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid.1 It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces apoptosis in T24 bladder cancer cells via production of reactive oxygen species.2 It also inhibits bacterial fatty acid dioxygenase with a Ki value of 49 nM in vitro.