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mPEG-SAA 的制备与纯化工艺
发布时间:2025-07-18     作者:kx   分享到:
文献综述:具备群聚引诱闪光的氧化的恢复备份太敏感高分子化合物物胶束使用生物工程激光散斑和*癌用药的递送连接://link.springer.com/article/10.1186/s12951-020-00761-9小编:孙长振,吉禄,王俊,郝平,李春红,陆奇,林杨何斌钟志荣&那好节选:mPEG-SAA的转化成将mPEG(0.2 g,0.1 mmol)和SAA(0.05 g,0.5 mmol)溶解60 mL无水二氯丁烷中,严重攪拌。冰浴下,将吡啶(0.4 mL)逐加入适度入分层物中。温度下攪拌48 h。在攪拌下,向不起作用管理体制中放入适度乙酸,以中合管理体制中转换的盐。油烟净化器祛除放置,蒸发器滤液,将粗品乙酰乙酸放置于一大批冷乙醚中。重复使用此纯化方法步骤多次,能够得到mPEG-SAA。

mPEG-SAA

Synthesis of mPEG-SAAThe mPEG (0.2 g, 0.1 mmol) and SAA (0.05 g, 0.5 mmol) were dissolved in 60 mL of anhydrous CH2Cl2 with strong stirring. Pyridine (0.4 mL) was added dropwise to the mixture on an ice bath. The mixture was stirred at room temperature for 48 h. An appropriate amount of acetic acid was added to the reaction system under stirring in order to neutralize salts produced in the system. The precipitate was removed by filtration, the filtrate was evaporated and the crude product was precipitated in a large volume of cold diethyl ether. This purification procedure was repeated several times to yield mPEG-SAA.渭南pg电子娱乐游戏app 生物体出示相关的厂品:DSPE-PEG-GE11(二硬脂酰基磷脂酰酒精胺-聚乙二醇-*内部表繁殖分子EGFR靶向治疗肽)DSPE-PEG-N3DSPE-PEG-RGD 二硬脂酰基磷脂酰乙酸乙酯胺-聚乙二醇-多肽DSPE-PEG-OX26 mAb(二硬脂酰基磷脂酰无水乙醇胺-聚乙二醇-*靶点核蛋白)Angiopep-2-PEG-DSPE大于优秀文章方面渠道各大杂志或论文参考文献,此事侵犯著作权请练习我误删!