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mPEG-EPO共聚AzPheEO制备及结构表征
发布时间:2025-07-16     作者:kx   分享到:
医学文献:聚乙二醇接枝光发应性聚乙二醇的合成视频与理论研究方法以及其在防生物制品污损软件应用工作方面的理论研究联接://www.mdpi.com/2073-4360/15/1/184我:马哈茂德·H·奥斯曼1,2奥西德,伊藤义弘1,2,3,*奥西德和秋元准节选:EO、AzPheEO和mPEG-EPO的共聚首选,将树脂乙烷 (EO) 与 AzPheEO 和 mPEG-EPO 共聚(方案范文 1)。所以,将 TBAB、AzPheEO 和 mPEG-EPO 在进口真空下低温吹干的 2 每H,而后暴晒于低温吹干的惰性气体中。将甲苯融入烧瓶中以融解 mPEG-EPO。自后,将 EO 盐水氢氧化钠水溶液和 i-Bu 3 Al 融入置放冰浴中的烧瓶中。将盐水氢氧化钠水溶液在 25 °C 下背光混合共聚 18 每H。将甲醇融入盐水氢氧化钠水溶液中,缓解压力洗除液体。将粗化学物质融解于甲苯中,并将盐水氢氧化钠水溶液自来水透析三四天。而后将得到整合反应物冷冻冰箱低温吹干的,称之为 AzPEGx [y],进来 x 和 y 各自代表着 Mn 和 mPEG-EO 的进料比。得到 AzPEGx [y] 整合反应物通过1 H-核磁共震 (NMR) 光谱分享法 (JNM-ECZ400R, 400 MHz, JEOL, 日式大阪) 在氯仿中采取定量分享,已经通过抑菌凝胶固化色谱法 (GPC; JASCO, 日式大阪) 采取定量分享。该操作系统具备几台折射率率的检测系统 (RI-2032, JASCO, 日式大阪) 和二根液相色谱柱 (SB-803 HQ 和 SB804 HQ; Showa Denko, 日式大阪),在包含 10 mM 溴化锂的二甲基甲酰胺 (DMF) 中采取分享。

mPEG-EPO

 Copolymerization of EO, AzPheEO, and mPEG-EPOFirst, EO was copolymerized with AzPheEO and mPEG-EPO (Scheme 1). For this, TBAB, AzPheEO, and mPEG-EPO were dried under vacuum for 2 h, after which they were exposed to dry nitrogen. Toluene was added to the flask to dissolve mPEG-EPO. Subsequently, the EO solution and i-Bu3Al were added to the flask in an ice bath. The solution was stirred for copolymerization at 25 °C in the dark for 18 h. Methanol was added to the solution, and the solvent was removed under reduced pressure. The crude compound was dissolved in acetone, and the solution was dialyzed against water for three days. The resulting polymer was then freeze-dried and is referred to as AzPEGx [y], where x and y represent the Mn and feed ratio of mPEG-EO, respectively. The obtained AzPEGx [y] polymer was characterized via 1H-nuclear magnetic resonance (NMR) spectroscopy (JNM-ECZ400R, 400 MHz, JEOL, Tokyo, Japan) in chloroform, as well as via gel permeation chromatography (GPC; JASCO, Tokyo, Japan). The system was equipped with a refractive index detector (RI-2032, JASCO, Tokyo, Japan) and two columns (SB-803 HQ and SB804 HQ; Showa Denko, Tokyo, Japan) in dimethylformamide (DMF) containing 10 mM lithium bromide.咸阳pg电子娱乐游戏app 怪物出示相关企业产品:DOPCDSPE-PEG-MannoseDSPE-PEG-RhodamineDOPE-PEG-SCDSPE(Sodium salt)-PEG-COOHDOPE-PEG-MalDSPE-PEG-多肽(各项定制网站)DSPE-PEG-Ce6超过论文资源渠道各学术期刊或参考文献,若有侵犯知识产权请连接让我们删去!