mPEG-S-S-COOH的合成方法
文章:AIE-Featured Redox-Sensitive Micelles for Bioimaging and Efficient Anticancer Drug Delivery诗人:by Wei Zhao 1,†,Zixue Li 1,†,Na Liang 2,*,Jiyang Liu 1,Pengfei Yan 1 andShaoping Sun 论文联结:了解:The conjugate mPEG-S-S-COOH was prepared by linking DTDPA with mPEG [39]. At first, DTDPA was synthesized as per a previous report [40]. Then DTDPA (96 mg), mPEG (500 mg), triethylamine (TEA, 70 μL), and 4-dimethylaminopyridine (DMAP, 61 mg) were added to N,N-dimethylformamide (DMF, 10 mL). The mixture was stirred at 35 °C. Twenty-four hours later, iced ethyl ether was added to precipitate the crude product. After solvent removal and further vacuum-drying, mPEG-S-S-COOH was isolated.