论文资料：PLGA-卵磷脂-PEG核壳纳米技术粒子束采用肝癌靶向治疗*下载链接：//www.worldscientific.com/doi/abs/10.1142/S1793984411000359笔者：郑明斌， 网球， 贾冬雪， 郑翠芳， 马一帆， 和 蔡林涛节选：英文论文你们了解一个多种多性能聚乳酸-乙酸乙酯酸共聚物 (PLGA)-卵磷脂-聚乙二醇 (PEG) 核壳nm塑料再生小粒剂 (NPs)，该nm塑料再生小粒剂兼备脂质体和汇聚物nm塑料再生小粒剂的缺点，可以使用于递送肺癌晚期放疗化疗中药。该nm塑料再生小粒剂的小粒剂直径、的漆层带电粒子和的漆层官能团可能够所有工序性能参数轻易设定，且反复重复性好，这类脂质/汇聚物、1,2-二硬脂酰-sn-甘油-3-磷酸乙酸乙酯胺 (DSPE)-PEG- COOH /卵磷脂、DSPE-PEG- COOH /DSPE-PEG- NH 2 的的质量比及及 DSPE-PEG 端基的体现。你们将模特肺癌晚期放疗化疗中药——亲水性树脂聚氨酯顺铂 (DDP) 或疏水性树脂聚氨酯 DDP 前药——封装类型于nm小粒剂 (NP) 中，结局体现 其包封率高、安全稳界定佳、对高 FA 蛋白激酶形容出的 MCF-7 组织体现了特男人靶向治疗中成药辨认意识，且 FA 蛋白激酶形容出量高，且组织致毒较小。这类 PLGA-卵磷脂-PEG 核壳nm小粒剂 (NP) 已被证实就是种*具竟争力的癌证靶向治疗中成药*中药递送nm媒介。AbstractWe reported the development of multifunctional poly (lactic-co-glycolic acid) (PLGA)-lecithin-polyethylene glycol (PEG) core-shell nanoparticles (NPs) that combined the beneficial properties of liposome and polymeric NPs for chemotherapeutics delivery. The particle size, surface charge and surface functional groups were easily tunable in highly reproducible manner by various formulation parameters such as lipid/polymer, 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEG-COOH/lecithin, DSPE-PEG-COOH/DSPE-PEG-NH2 mass ratio and modification of terminal groups of DSPE-PEG. We encapsulated model chemotherapy drug, hydrophilic cisplatin (DDP) or hydrophobic DDP prodrug, in the NPs and showed high encapsulation efficiency, excellent stability, specific FA targeting recognition for MCF-7 cells with over FA receptors expression and pretty cytotoxicity. Such PLGA–lecithin–PEG core-shell nanoparticles (NPs) were proved to be a promising drug delivery nanocarrier for cancer-targeted therapy.

绵阳pg电子娱乐游戏app 生物工程作为相关联厂品：DSPE-PEG-PLADSPE-PEG-THDPPE-PEG-NH2DSPE-PEG-LTVSPWY（二硬脂酰基磷脂酰无水乙醇胺-聚乙二醇-*靶向疗法血清)FITC-Angiopep-2-PEG-DSPEDSPE-Poly(L-lysine)C18-PEGn-COOHDSPE(Sodium salt)-PEG-COOHiRGD-PEG-MALDSPE-PEG-NGRDSPE-PEG-Progestrone上文一篇文章相关内容从何而来各杂志期刊或论文参考文献，假如有版权侵权请电话联系他们删掉！