DSPE-PEG-OH的合成与结构表征
论文:胃黏膜吸附力脂质体递送设计联合*炎和*被氧化功用强化对干眼病的*图片链接://www.sciencedirect.com/science/article/abs/pii/S0168365924001391写作者:黄 可欣,荣 国 ,浩源 罗阿 ,刘厚 勤,东辰 ,邓涛 ,李嘉欣 ,焦 河 阿,徐 祝平,曼丽 啊,秦 禾节选:CsA/Cro PBA 唇膜的光催化原理及定性分析DSPE-PEG-PBA 的分解成风格如同 S1表达。确认酰化生理反应,4-羧基-3-氟苯基硼酸胜利连接方式到 DSPE-PEG-NH 2 上[50]。DSPE-PEG-PBA 的化学物质结构设计确认1 H NMR定量分析。如同 S2表达,在 DSPE-PEG-PBA 的谱图示,9.5 ppm 处 4-羧基-3-氟苯基硼酸的羧基峰失踪,而在 7.5~8.0 ppm 处考察到 PBA 上苯环和酰胺键的本质特征峰Preparation and characterization of the CsA/Cro PBA lipThe synthetic route of DSPE-PEG-PBA is shown in Fig. S1. Through acylation reaction, 4-Carboxy-3-fluoro-phenylboronic acid was successfully linked to DSPE-PEG-NH2 [50]. The chemical structure of DSPE-PEG-PBA was characterized by 1H NMR. As shown in Figs. S2, in the spectrum of DSPE-PEG-PBA, the carboxyl peak of 4-carboxy-3-fluoro-phenylboronic acid at 9.5 ppm disappeared, while the characteristic peaks of the benzene ring on PBA and the amide bond were observed at 7.5–8.0 ppm