英语翻译名称大全：Monobromobimane(mBBr)

 Bromobimane

3-(Bromomethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

中文版名字大全：溴代双满，溴二胺

3-(溴甲基)-2,5,6-三级甲等基吡唑并[1,2-a]吡唑-1,7-二酮

CAS NO：71418-44-5

MDL number：MFCD00036951

大分子结构：C10H11BrN2O2

团伙量：271.11

纯  度：≥95.0%

采用简绍：

单溴二胺不是种巯基发应的荧光电极，兼具组织细胞渗性，生理性pH下与遇到到的巯基基团快捷发应，所产生同一个动态平衡的荧光信号灯。mBBr可以来评价或参考值深入研究表含特异性硫或巯基基团的有机物，是指加硫氢（H2S），谷胱甘肽，蛋白质和核苷酸。尤其适于用在谷胱甘肽的参考值。mBBr的*吸纳和释放出光波长分別为395nm和490nm。

Bromobimanes in solution (aqueous or organic solvents of medium polarity) react with small thiols [e.g., the tripeptide thiol glutathione (GSH)], and with reactive protein thiol groups (e.g., hemoglobin). The reactions of bromobimanes with thiols are second order and dependent on pH, the active nucleophile being the thiolate anion. The reaction of bromobimane with a thiolate converts the nonfluorescent agent into water-soluble fluorescent products. The neutral agents mBBr and bBBr are moderately soluble in mediumpolarity organic solvents (acetonitrile, dichloromethane), and slightly soluble in water. The quaternary salt, qBBr, and the anionic bromobimane, SBBr, are soluble in water, but less soluble in organic solvents. Bromobimanes are yellow[1]. The highly selective, rapid reactivity of bromobimanes toward thiols, the stability and fluorescence yield of the thiol derivatives, the ease of separation of the derivatives by reversed-phase HPLC, and the availability of both cell-penetrating and nonpenetrating forms, make the use bromobimanes an extremely powerful approach to the analysis of low molecular weight biothiols. 

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